Insights

Explore the latest insights in chemical proteomics, target engagement, and drug discovery. Read scientific perspectives, research updates, and company news from our team.

Activity-based protein profiling & serine hydrolases

Activity-based protein profiling & serine hydrolases

Activity-based Protein Profiling was first introduced in 1999 in a seminal paper by the group of Benjamin Cravatt. The idea is beautiful in its simplicity: turn covalent inhibitors (sometimes called ‘suicide substrates’) into a ‘probe’, a molecule that can be...

Activity-based protein profiling & serine hydrolases

Activity-based protein profiling & serine hydrolases

Activity-based Protein Profiling was first introduced in 1999 in a seminal paper by the group of Benjamin Cravatt. The idea is beautiful in its simplicity: turn covalent inhibitors (sometimes called ‘suicide substrates’) into a ‘probe’, a molecule that can be...