Accelerating drug discovery through chemical proteomics

Generate biologically relevant target-engagement data before costly downstream decisions

Most drug discovery decisions are still based on data generated outside biological reality.

Omivera helps biotech and pharmaceutical companies make better small-molecule development decisions through chemical proteomics.

Generate target engagement, selectivity, and mechanism-of-action insights before costly downstream studies.

We help you
see more

By the time a compound reaches lead optimization, uncertainty becomes expensive. Traditional assays provide part of the picture.

You need to know:

Is my compound engaging its target?
Are there unexpected off-target effects?
Is the mechanism of action clear?
Is evidence strong enough to proceed?

At Omivera, we use chemical proteomics to help you understand how compounds interact with proteins in biologically relevant systems.

Rather than relying solely on artificial assay conditions, you gain insight into target engagement, selectivity, protein activity, and mechanism of action in a setting that better reflects biological reality. The result is stronger evidence to support critical development decisions during lead optimization and preclinical development.

1. Hit identification

You are exploring early kinase inhibitor candidates and need a first view of cellular target engagement.

2. Lead Optimization

You are selecting lead candidates and need confidence in selectivity, mechanism, and off-target behavior.

3. Preclinical Development

You are preparing for in vivo studies and need biologically relevant data before major downstream investment

4. Translational & In Vivo Studies

You are evaluating compound behavior in more complex biological systems and translational models.

Many critical drug-target interactions cannot be fully understood through biochemical assays alone.

Chemical proteomics enables direct measurement of compound behaviour in biologically relevant systems, helping you move forward with greater confidence.

→ Understand target engagement

→ Assess selectivity

→ Identify off-target interactions

→ Investigate mechanism of action

→ Support candidate prioritization

Every development
challenge requires a
different perspective.

Our platform portfolio helps you answer a wide range of drug discovery questions through biologically relevant protein-level insights.

CellEKT

Measure target engagement across the kinome in biologically relevant systems. CellEKT is Omivera’s proprietary platform for measuring target engagement across the kinome using chemical proteomics..

Activity-Based Protein Profiling (ABPP)

Characterize active enzyme populations and understand how compounds influence protein activity.

Residue-Specific Proteomics

Investigate compound interactions at the amino acid level.

Probe-Enabled Workflows

Tailored chemical proteomics studies designed around your scientific question.

Ensure every development decision is guided by biology that actually matters.

Joel Rüegger, CEO

Whether you’re advancing a promising lead, investigating unexpected results, or preparing for the next stage of development, Omivera helps you reduce uncertainty through better biological insight.